Donor Network of Arizona

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Improving Organ Donation Outcomes through NRP

Home Improving Organ Donation Outcomes through NRP

One of the technologies that has been improving the outcomes from donation after circulatory death (DCD) donors recently in the U.S., and more routinely in Europe over the past decade, is the use of normothermic regional perfusion (NRP). Donor Network of Arizona (DNA) has participated in NRP with organ transplant center partners (when requested) for almost three years, including centers from Arizona, California, Utah and Tennessee. This use of NRP in Arizona has benefited recipients from almost 30 donors.

DNA is working to make NRP more common on DCD donors in Arizona through a contract with a local perfusion provider. We would like to share information about this emerging process, how it works, how it will provide more lifesaving organs for transplant, and how it honors the gifts given by donors and their families.

Please watch the webinar recording and see FAQs below for more information! Please contact your Donor Program Development coordinator with any further questions.

webinar

Click here to download the webinar slides.

Faqs

Click here to download a flyer with this information.

What is NRP?

NRP is a recovery technique that utilizes in-situ perfusion of specific organs for transplant, allowing for improved stewardship of the donor’s gift and providing hope to those in need of a lifesaving transplant.

Upon declaration of death, isolated perfusion and oxygenated blood is reestablished to the thoracic and/or abdominal area. The cerebral arteries are clamped and vented to prevent brain perfusion and the aorta and right atrium are cannulated.

Benefits

  • Mitigates the detrimental impact of warm ischemic time
  • Increases the number of organs otherwise not transplanatable
  • Improves organ function
  • Improves organ recipient outcomes

OR Specifics

  • Patient is extubated, cardiac death is declared and donor is promptly moved to OR
  • NRP team will arrive prior to recovery to ensure proper equipment set up
  • Hospital OR will determine location and storage of PRBCs (4-5 units)
  • Hospital OR will need to take into consideration anesthesia availability

Register to Save and Heal Lives

Heart recipient, Greg Welsh, and the mother of his donor, Alejandra Rivera, share a special bond through Fernando Rivera’s lifesaving gift. Fernando saved three others as an organ donor after passing away in 2011.

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